TURİSTİK DESTİNASYON ÇERÇEVESİNDE SÜRDÜRÜLEBİLİR TURİZM YÖNETİMİVE PAZARLAMASI

Bu çalışmada turistik destinasyonlarda sürdürülebilir turizm yönetimi ve pazarlamasıperspektiflerinden genel olarak bahsedilmiştir. Sürdürebilirliğin temelinde, turizm kaynaklarının bugün ve gelecekte kullanımıile ilgili bilincin önemi yatmaktadır. Turizm yönetimi anlayışınıkullanarak turizm kaynaklarınıdeğerlendirmek, eko turizm kıstaslarıile sürdürebilir bir büyüme sağlamak önem taşımaktadır. Bu çalışmada sürdürülebilir turizm yönetim ve pazarlama anlayışına dikkat çekilmiştir. Çalışma derleme niteliğinde olup; sürdürülebilirlik açısından yönetsel süreçte çevre-insan iletişiminde turizm kaynaklarının tanıtımının yapılması, kaynakların kullanımı, potansiyel müşteriler ve yerel halkla ilişkileri, turistikdestinasyonların pazarlamasıve sürdürülebilir turizm yönetimi içerisinde değerlendirilmektedir

Análisis de algunos aspectos físicos, químicos y microbiológicos de las muestras de miel producidas y consumidas en Turquía

Analysis of honey produced in the western part of Turkey was carried out in this study. Fifty honey samples, collected from the local market in this region were analyzed for their physicochemical parameters including hydroxymethylfurfural (HMF), electrical conductivity, sucrose, free acidity, moisture and water insoluble impurities, in addition to pathogenic microorganisms present. HMF amounts determined in 47 samples were found to be between 1.9 and 98.0 mg/kg with good reproducibilities (%RSD: 3.2% or better). There were no pathogenic microorganisms in any of the investigated samples. Electrical conductivity that gives information about their mineral contents was measured, and the mean value was found to be 0.33 mS/cm (N=34). In general, most of the samples were considered to meet the requirements of Turkish Food Codex and European Commission Directives.En este estudio se analizó muestras de miel producida en la zona oeste de Turquía. Se trabajó con 50 muestras del mercado local de la región, en las cuales se determinaron parámetros físico-químicos incluyendo el hidroximetilfurfural (HMF), conductividad eléctrica, sacarosa, acidez libre, humedad e impurezas insolubles en agua además de microorganismos patógenos presentes. Las cantidades de HMF determinadas en 47 muestras oscilaron entre 1,9 y 98,0 mg/kg con buena desviación estándar de la reproducibilidad (% de RSD/DSR 3,2% o mejor). No se encontraron microorganismos patógenos en ninguna de las muestras analizadas. La conductividad eléctrica, que aporta información sobre el contenido mineral, resulta en un promedio de 0,33 mS/cm (N=34). En general se encontró que la mayoría de las muestras cumple los requerimientos del Codex alimentario turco y de las directivas de la Comisión Europea.Fil: Bakirdere, Sezgin. Universidad Técnica de Yıldız (Turquía)Fil: Yaroglu, Tolga. Universidad de Ankara (Turquía)Fil: Tirik, Nihan. Ondokuz Mayıs University (Turquía)Fil: Demiroz, Mehmet. Uludag University (Turquía)Fil: Karaca, Abdullah. Fırat University (Turquía

Enhanced secure data transfer for WSN using chaotic-based encryption

Postupci na bežičnim senzorskim mrežama - Wireless Sensor Networks (WSN) i njihovim područjima uporabe sve su češći pa problem sigurnosti mreže postaje sve važniji. Budući da su snaga procesora, memorija i izvori energije ograničeni na čvorove bežičnih senzorskih mreža, tradicionalno strukturirani kodovi više nisu učinkoviti. Uzevši to u obzir, očita je potreba za manjim procesnim opterećenjem i potrošnjom energije te učinkovitim kodom. U ovom se radu razvija kaotični kodni sustav za zadovoljenje sigurnosnih potreba na WSN. Uspoređuju se ovdje razvijeni kaotični sustav i uobičajeno korišteni Skipjack kod uz pomoć algoritma OPNET Modeller softvera i konstatira se da su postignuti bolji rezultati.Processes on Wireless Sensor Networks (WSN) and their areas of use have become more widespread, and the issue of net-work security has appeared as one of the primary necessities. As power of the processor, memory and energy sources are limited on wireless sensor network nodes, traditional encryption structures are not found effective. With these criteria taken into consideration, the need for less process load and energy consumption as well as a powerful encryption is obvious. In this study, a chaotic encryption system to meet the security need on WSN using chaotic systems was carried out. The chaotic system developed here and the commonly used Skipjack encryption were compared with the help of algorithm OPNET Modeller software and better results were achieved

ADEA Claimant Can Retain Severance Payments and Sue Former Employer

Former employees can maintain claims under the Age Discrimination in Employment Act (ADEA) without first repaying the consideration received for an invalid release of claims. The Supreme Court\u27s pronouncement, Oubre v. Entergy Operations, Inc., 1988 U.S. Lexis 646 (Jan. 26, 1998), may change the way many employers negotiate and execute severance packages and settlements with terminated employees

The marine arthropods of Turkey

This recent checklist of marine arthropods found on the coasts of Turkey represents a total of 1531 species belonging to 7 classes: Malacostraca (766 species), Maxillopoda (437 species), Ostracoda (263 species), Pycnogonida (27 species), Arachnida (26 species), Branchiopoda (7 species), and Insecta (5 species). Seventy-fve species were classifed as alien species in the region. Tis paper also includes the frst record of the amphipod Melita valesi from the Levantine coast of Turkey (Kaş, Gulf of Antalya).This recent checklist of marine arthropods found on the coasts of Turkey represents a total of 1531 species belonging to 7 classes: Malacostraca (766 species), Maxillopoda (437 species), Ostracoda (263 species), Pycnogonida (27 species), Arachnida (26 species), Branchiopoda (7 species), and Insecta (5 species). Seventy-fve species were classifed as alien species in the region. Tis paper also includes the frst record of the amphipod Melita valesi from the Levantine coast of Turkey (Kaş, Gulf of Antalya)

A Clinical Experience: Endoscopic and Surgical Management of Bezoars

Objective:This study aims to evaluate the cases treated for gastrointestinal obstruction due to bezoar in terms of clinical-radiological-endoscopic features and treatment methods.Method:Among the patients treated for acute mechanical intestinal obstruction (AMIO) in our hospital between January 2014 and December 2019, 33 patients with bezoar-related AMIO were included in the study. The cases were examined in terms of the presence of comorbidity, tomography and endoscopy features, and treatment modalities.Results:A history of intraabdominal surgery was found in 82% of patients (n=27) and a history of upper gastrointestinal surgery in 60% (n=20). DM accompanied in 27% of the patients (n=9) and psychiatric disorder in 18% (n=6). With computered tomography, gastric dilatation was observed in 9 patients, jejunal in 9 patients, jejunoileal in 9 patients, and dilatation in all bowel segments in 6 patients. Endoscopy was performed in 12 patients; 9 had peptic ulcers, 3 were normal. Seventeen cases were treated with laparotomy, 9 cases with a laparoscopic enterotomy, and 3 cases with endoscopic procedures. 4 cases were treated with a Coca-Cola injection from a nasogastric catheter, which was successful.Conclusion:It is difficult to diagnose bezoar-related AMIO with clinical findings. Radiological and endoscopic methods are important in diagnosis. Although endoscopic methods are also used successfully for therapeutic purposes, surgical methods are used in distal locations and complicated cases

Determination of As, Cd, and Pb in tap water and bottled water samples by using optimized GFAAS system with Pd-Mg and Ni as matrix modifiers

Arsenic, lead and cadmium were determined in tap and bottled water samples consumed in the west part of Turkey at trace levels. Graphite Furnace Atomic Absorption Spectrometry (GFAAS) was used in all detections. All of the system parameters for each element were optimized to increase sensitivity. Pd-Mg mixture was selected as the best matrix modifier for As while the highest signals were obtained for Pb and Cd in the case of Ni used as matrix modifier. Detection limits for As, Cd, and Pb were found to be 2.0, 0.036 and 0.25 ng/mL, respectively. 78 tap water and 17 different brands of bottled water samples were analyzed for their As, Cd and Pb contents under the optimized conditions. In all water samples, concentration of cadmium was found to be lower than detection limits. Lead concentration in the samples analyzed varied between N.D. and 12.66 +/- 0.68 ng/mL. The highest concentration of arsenic was determined as 11.54 +/- 2.79 ng/mL. Accuracy of the methods was verified by using a certified reference material namely Trace Element in Water, 1643e. Results found for As, Cd, and Pb in reference materials were in satisfactory agreement with the certified values

The 33-year Retrospective Analysis of Esophageal Carcinomas: Cerrahpaşa Experience

Aim:Esophageal cancer is a fatal disease where the majority of patients are diagnosed at an advanced stage. In this study, we aimed to present the demographic and clinicopathological characteristics of patients who were operated for esophageal cancer.Materials and Methods:A total of 847 patients who underwent surgery, chemoradiotherapy, or palliative procedures for esophageal pathology between the years of 1985 and 2018 were retrospectively analyzed. Age, gender, tumor location, histopathology, surgical technique, and chemoradiotherapy history of patients were analyzed.Results:In the study, 488 patients were male (60.5%) and 319 were female (39.5%). The ratio of males and females was 1.52. The average age was 58.6 years, and 80.1% were older than 50 years. The most common pathological material obtained was squamous cell carcinoma (67.5%), followed by adenocarcinoma (27.7%). Total esophagectomy was performed in 435 patients; distal esophagectomy was performed in 38 patients. Transhiatal esophagectomy (n=271, 62.2%) was the most common procedure that was performed.Conclusion:Esophagectomy is the primary treatment modality for esophageal cancers. When determining the optimal treatment, appropriate patient selection, staging, and risk assessment should be made. Patient-specific treatment should be planned with a multidisciplinary approach

Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy

Background: There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which subsequent treatment oncologists prefer in patients with disease progression under CDKi. In addition, we aimed to show the effectiveness of systemic treatments after CDKi and whether there is a survival difference between hormonal treatments (monotherapy vs. mTOR-based). Methods: A total of 609 patients from 53 centers were included in the study. Progression-free-survivals (PFS) of subsequent treatments (chemotherapy (CT, n:434) or endocrine therapy (ET, n:175)) after CDKi were calculated. Patients were evaluated in three groups as those who received CDKi in first-line (group A, n:202), second-line (group B, n: 153) and ≥ 3rd-line (group C, n: 254). PFS was compared according to the use of ET and CT. In addition, ET was compared as monotherapy versus everolimus-based combination therapy. Results: The median duration of CDKi in the ET arms of Group A, B, and C was 17.0, 11.0, and 8.5 months in respectively; it was 9.0, 7.0, and 5.0 months in the CT arm. Median PFS after CDKi was 9.5 (5.0–14.0) months in the ET arm of group A, and 5.3 (3.9–6.8) months in the CT arm (p = 0.073). It was 6.7 (5.8–7.7) months in the ET arm of group B, and 5.7 (4.6–6.7) months in the CT arm (p = 0.311). It was 5.3 (2.5–8.0) months in the ET arm of group C and 4.0 (3.5–4.6) months in the CT arm (p = 0.434). Patients who received ET after CDKi were compared as those who received everolimus-based combination therapy versus those who received monotherapy ET: the median PFS in group A, B, and C was 11.0 vs. 5.9 (p = 0.047), 6.7 vs. 5.0 (p = 0.164), 6.7 vs. 3.9 (p = 0.763) months. Conclusion: Physicians preferred CT rather than ET in patients with early progression under CDKi. It has been shown that subsequent ET after CDKi can be as effective as CT. It was also observed that better PFS could be achieved with the subsequent everolimus-based treatments after first-line CDKi compared to monotherapy ET.Breast Cancer Consortiu